Research Use Only: Intended for in-vitro laboratory research only. Not for human or animal consumption. This page provides mechanistic and research-context information only — it does not constitute dosing, administration, or medical advice of any kind.
SS-31
A mitochondria-targeted peptide that's one of the most studied compounds for mitochondrial membrane research and oxidative stress studies.
SS-31 (elamipretide) is a synthetic aromatic-cationic tetrapeptide that associates with the inner mitochondrial membrane (cardiolipin). It is used in mitochondrial-membrane, bioenergetics and oxidative-stress research.
Targets mitochondrial membranes
Research shows oxidative stress reduction
One of the most studied mitochondrial compounds
May support cellular energy
- Mechanism
Scientific Mechanism
This class of compounds targets mitochondrial function, oxidative stress pathways, and cellular senescence markers. Mechanisms studied include mitochondrial membrane stabilization, sirtuin-pathway activation via NAD+ availability, and telomerase-related signaling — all active areas of longevity and cellular-aging research.
- Mechanism detail
How It Works
SS-31 works through mitochondrial targeting:
targeting:
Specifically targets mitochondrial membranes
oxidative:
Reduces oxidative stress in mitochondria
energy:
Supports cellular energy production
- Research evidence
What the Research Shows
Mitochondrial:
- Longevity & Mitochondrial Research
Research Applications
Investigated in in-vitro models for cellular senescence, mitochondrial function, and longevity pathways.
- Research notes
Key Research Points
- Studied for mitochondrial targeting, oxidative stress reduction, and cellular energy restoration.
- Mitochondria-targeted tetrapeptide (CAS 736992-21-5)
- Lot-level documentation and Certificate of Analysis
Common Questions
- Laboratory context
Research Considerations
- For in-vitro laboratory research use only
- Not for human or animal consumption
- Verify identity and purity against the lot Certificate of Analysis
- Handle with standard laboratory PPE and aseptic technique
- Storage & handling
Stability Protocol
Lyophilized powder: store at -20°C with desiccant, protected from light. Reconstituted solution: refrigerate at 2–8°C, discard after 28–30 days or if cloudiness/particulate appears.
- Reconstitution math
Concentration Calculator
Concentration math only — for research reference. Not dosing guidance.
- Verification
Certificate of Analysis
Research Use Only: Intended for in-vitro laboratory research only. Not for human or animal consumption. This page provides mechanistic and research-context information only — it does not constitute dosing, administration, or medical advice of any kind.