Research Use Only: Intended for in-vitro laboratory research only. Not for human or animal consumption. This page provides mechanistic and research-context information only — it does not constitute dosing, administration, or medical advice of any kind.
TB-500
A fragment of Thymosin Beta-4, a naturally occurring peptide that plays a role in cell migration, inflammation, and tissue repair.
TB-500 is a synthetic peptide based on the actin-binding region of Thymosin β4. It is used in research on actin polymerisation, cell migration and tissue-remodeling models.
Derived from Thymosin Beta-4
Often paired with BPC-157
CAS 77591-33-4
Thymosin β4 peptide
- Mechanism
Scientific Mechanism
Cytoprotective and repair-signaling peptides in this class act through angiogenesis promotion, fibroblast activation, and growth-factor upregulation. Several also modulate NF-kB and cytokine signaling, which is why tissue-repair and anti-inflammatory research frequently overlap in this category.
- Mechanism detail
How It Works
TB-500 works through actin regulation and cell migration:
actin:
Regulates actin polymerization for cell movement
migration:
Helps cells migrate to damaged tissues
repair:
Supports the overall repair process
- Research evidence
What the Research Shows
Tissue Repair:
Inflammation:
- Musculoskeletal & Tissue Repair
Research Applications
Researched in in-vitro models of actin regulation, cell migration, and tissue remodeling.
- Research notes
Key Research Points
- Researched for actin regulation, cell migration, and tissue remodeling in regenerative medicine studies.
- Thymosin β4 peptide (CAS 77591-33-4)
- Lot-level documentation and Certificate of Analysis
Common Questions
- Laboratory context
Research Considerations
- For in-vitro laboratory research use only
- Not for human or animal consumption
- Verify identity and purity against the lot Certificate of Analysis
- Handle with standard laboratory PPE and aseptic technique
- Storage & handling
Stability Protocol
Lyophilized powder: store at -20°C with desiccant, protected from light. Reconstituted solution: refrigerate at 2–8°C, discard after 28–30 days or if cloudiness/particulate appears.
- Reconstitution math
Concentration Calculator
Concentration math only — for research reference. Not dosing guidance.
- Verification
Certificate of Analysis
Research Use Only: Intended for in-vitro laboratory research only. Not for human or animal consumption. This page provides mechanistic and research-context information only — it does not constitute dosing, administration, or medical advice of any kind.