Research Use Only: Intended for in-vitro laboratory research only. Not for human or animal consumption. This page provides mechanistic and research-context information only — it does not constitute dosing, administration, or medical advice of any kind.
Tesamorelin
Tesamorelin is a synthetic analogue of human growth-hormone-releasing hormone (GHRH 1-44) stabilised by an N-terminal trans-3-hexenoyl group, used in GHRH-receptor and GH-axis research.
Tesamorelin is a synthetic analogue of human growth-hormone-releasing hormone (GHRH 1-44) stabilised by an N-terminal trans-3-hexenoyl group, used in GHRH-receptor and GH-axis research.
Stimulates natural growth hormone release
Research shows effects on body composition
One of the most studied compounds in its class
CAS 218949-48-5
- Mechanism
Scientific Mechanism
These compounds act on the growth-hormone axis via GHRH-receptor or ghrelin-receptor (GHS-R) pathways in the pituitary, or via downstream IGF-1 signaling. Receptor activation stimulates pulsatile GH release, which is studied for its effects on body composition, cellular repair signaling, and endocrine research models.
- Mechanism detail
How It Works
Tesamorelin works through GHRH receptor activation:
ghrh:
Binds to GHRH receptors in the pituitary gland
pituitary:
Stimulates pulsatile growth hormone release
igf:
Increases IGF-1 production (a key growth factor)
- Research evidence
What the Research Shows
Growth Hormone:
Body Composition:
- GH Axis & Endocrine Research
Research Applications
Studied in in-vitro models for metabolic regulation, receptor pathway activation, and cellular energetics.
- Research notes
Key Research Points
- Studied for GHRH receptor activation, growth hormone release, and endocrine tissue research applications.
- GHRH analogue (CAS 218949-48-5)
- Lot-level documentation and Certificate of Analysis
Common Questions
- Laboratory context
Research Considerations
- For in-vitro laboratory research use only
- Not for human or animal consumption
- Verify identity and purity against the lot Certificate of Analysis
- Handle with standard laboratory PPE and aseptic technique
- Storage & handling
Stability Protocol
Lyophilized powder: store at -20°C with desiccant, protected from light. Reconstituted solution: refrigerate at 2–8°C, discard after 28–30 days or if cloudiness/particulate appears.
- Reconstitution math
Concentration Calculator
Concentration math only — for research reference. Not dosing guidance.
- Verification
Certificate of Analysis
Research Use Only: Intended for in-vitro laboratory research only. Not for human or animal consumption. This page provides mechanistic and research-context information only — it does not constitute dosing, administration, or medical advice of any kind.